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Friday, January 10, 2025

This Silent Illness Impacts Hundreds of thousands of People


In accordance with the U.S. Division of Well being and Human Companies, round 10 million folks over the age of fifty have osteoporosis. An extra 43 million have low bone mineral density, placing them in danger for full-blown osteoporosis.1 It is a regarding quantity of people that have compromised skeletal well being, as osteoporosis will increase your threat of main fractures.

Recognizing the Indicators of Osteoporosis

Osteoporosis is known as the “silent illness” as a result of it would not current any signs till you endure a fracture.2 However because it progresses, you will discover gradual modifications in your physique that point out lack of skeletal rigidity:3

Lowering top

Rounded shoulders

Creating hump on the again

Head begins to protrude ahead

Intermittent or fixed higher, center and/or decrease again ache

Noticeable modifications in physique form

What causes this silent illness to happen within the first place? As you age, your physique breaks down bone tissue sooner than it replenishes,4 and this course of is influenced by numerous components. Examples embody your eating regimen (whether or not you are getting the suitable minerals or not), stage of bodily exercise, hormonal modifications and any drugs you are taking. Unhealthy habits reminiscent of smoking and heavy alcohol consumption have an effect on your bone well being, too.5

Medical doctors usually suggest a bone density scan when you’ve gotten a household historical past of osteoporosis, or for those who’re over 50 years previous.6 The commonest methodology of figuring out osteoporosis is a DEXA (dual-energy X-ray absorptiometry) scan, which measures bone mineral density. Nonetheless, as I’ve famous in my latest article “The Nice Osteoporosis Rip-off,” as soon as osteoporosis is identified, docs will usually prescribe medicine that do extra hurt than good.

The Downside with Osteoporosis Medication

When a health care provider confirms an osteoporosis prognosis, the usual remedy is a prescription for bisphosphonates (Fosamax or Actonel), which inhibit osteoclasts (cells that break down bone).7 Whereas the intention is sweet, there are two main issues:

  • Bisphosphonates will disrupt your physique’s bone-building course of, ensuing within the preservation of “previous bone” somewhat than selling wholesome bone formation by way of pure strategies (extra on this later)
  • Bisphosphonates have unwanted side effects,8 such extreme musculoskeletal ache

In case you had been to take bisphosphonates, you will most likely see an enchancment in your DEXA scan rating. However that will not deal with the basis reason behind osteoporosis and will not contribute to the long-term enchancment of your bone mineral density.

Proton-pump inhibitors (PPIs), a category of medicine designed to alleviate heartburn signs, are one of the crucial generally pharmaceuticals in the USA,9 they usually contribute to the ever-growing osteoporosis epidemic as properly. Loads of revealed analysis have proven that PPIs negatively have an effect on bone density by:

  • Inducing hypochlorhydria (a state the place manufacturing of hydrochloric acid manufacturing is absent or very low), which inhibits calcium absorption10
  • Dysregulating bone resorption, which is crucial for wholesome bone11
  • Intestine microbiome alterations leading to altered mineral absorption12
  • Inflicting hypomagnesemia (low magnesium)13

Analysis reveals that PPIs additionally have an effect on bone well being by affecting collagen synthesis. As famous in a 2020 research revealed within the Frontiers in Endocrinology:14

“PPIs may very well goal the ECM [extracellular matrix] on the whole and members of the collagen household particularly to affect bone pathophysiology together with growing the chance of osteoporosis and osteoporotic fractures …”

The Interaction Between Calcium and Vitamin D

In relation to selling bone well being, it is necessary to begin on the supply — addressing nutrient deficiencies that contribute to weakened bones. An awesome place to begin is growing calcium, since virtually 98% of this mineral current in your physique is present in your bones.

Your physique always wants calcium as a result of your bones repeatedly rework themselves.15 So, how a lot calcium does your physique want? Listed here are the really helpful intakes, in keeping with the Workplace of Dietary Dietary supplements:16

Age Male Feminine
0 to six months 200 mg 200 mg
7 to 12 months 260 mg 260 mg
1 to three years 700 mg 700 mg
4 to eight years 1,000 mg 1,000 mg
9 to 13 years 1,300 mg 1,300 mg
14 to 18 years 1,300 mg 1,300 mg
19 to 50 years 1,000 mg 1,000 mg
51 to 70 years 1,000 mg 1,200 mg
Over 70 years 1,200 mg 1,200 mg

One of the best sources of calcium are milk and dairy merchandise, ideally from grass fed cows. Yogurt, cheese and kefir are nice selections. Consuming uncooked milk by itself is one other nice choice.

One other very important piece of the equation is optimizing your vitamin D ranges. Analysis has proven that vitamin D performs a job in serving to with calcium absorption, and that boosting vitamin D ranges helps enhance bone mineral density.17

One of the best ways to spice up vitamin D ranges is by getting common daylight publicity, ideally throughout photo voltaic midday when UVB rays are at their peak. To be sure to’re on the correct path, have your blood examined too. For optimum well being, intention for a spread between 60 ng/mL and 80 ng/mL of vitamin D in your blood.

However earlier than you exit for some daylight, there are caveats that you’ll want to think about. For instance, for those who’ve been consuming a eating regimen excessive in linoleic acid (LA), then it is not secure so that you can exit at peak midday.

When daylight hits your pores and skin, it can oxidize and break down the LA embedded there, inflicting irritation and DNA harm. Excessive LA consumption is usually the trigger for those who burn quickly. The logical strategy is to drastically scale back the LA in your physique, which takes as much as six months. Purpose for a each day LA consumption of lower than 5 grams. If you will get beneath 2 grams, that is even higher.

Throughout this transition interval, restrict your solar publicity to early morning or late afternoon. To guard your pores and skin, I additionally suggest taking:

• Niacinamide — Also called nicotinamide, a type of vitamin B3, will assist towards DNA harm attributable to ultraviolet gentle publicity.

• Low-dose aspirin — Taking a small quantity of aspirin 30 to 60 minutes earlier than going underneath the solar helps forestall LA from turning into oxidized linoleic acid metabolites (OXLAMs), a major contributor to irritation and illness.

• Molecular hydrogen — This potent molecule reduces oxidative stress by eliminating dangerous free radicals all through your system.

Do not Neglect Magnesium and Vitamin K2

Rounding out the vitamins wanted to fight osteoporosis are magnesium and vitamin K2. Analysis has proven that magnesium deficiency results in brittle, fragile bones that result in microfractures. Furthermore, magnesium is required to stimulate osteoblastic exercise, and it influences skeletal homeostasis regulators — parathyroid hormone and vitamin D.18

As for vitamin K2, research have proven that it promotes osteogenic differentiation. In different phrases, it directs your physique to advertise extra wholesome bone formation as a substitute of failure. It additionally promotes osteoclastic resorption by suppressing osteoclast exercise.19

Now that you recognize the significance of magnesium and vitamin K2, what are one of the best dietary sources? For magnesium, ideally suited sources embody greens, reminiscent of spinach, broccoli and carrots.20

In the meantime, vitamin K2 is present in fermented meals reminiscent of sauerkraut, kefir, cheese and yogurt.21 For an in-depth rationalization of the really helpful dosages for every nutrient (calcium, vitamin D and K2, and magnesium) for optimum outcomes, learn my article “Is Magnesium the Lacking Hyperlink in Your Coronary heart Wholesome Routine?”

Bones Additionally Want Protein, Particularly Collagen

Amino acids, that are synthesized into protein, kind the constructing blocks of your physique. Whereas most individuals consider protein by way of muscle constructing, your complete physique makes use of it in a roundabout way, together with your bones. Actually, the human skeleton incorporates loads of protein, significantly collagen for its elasticity.

Sufficient collagen offers your bones “cushion,” serving to them bend and yield to exterior forces as a substitute of fracturing. As famous in a research revealed in Journal of Frailty, Sarcopenia & Falls:22

“Collagen and quite a lot of noncollagenous proteins kind the natural matrix of bone, so an satisfactory dietary protein consumption would appear to be important for optimum acquisition and upkeep of grownup bone mass.”

For optimum bone well being, you want a steadiness of muscle meat and collagen amino acids. Pink meat incorporates little or no of the health-promoting amino acids (highlighted in inexperienced), which signifies that relying solely on muscle meat will probably be inadequate for constructing robust connective tissues and sustaining bone power.

Moreover, whereas the three major amino acids in collagen are related to anti-inflammatory and different well being advantages, these discovered abundantly in purple meat (highlighted in purple) promote irritation.

amino acid ratios of gelatin and collagen versus red meat

I like to recommend you get one-third of your protein consumption from collagen or gelatin as a result of solely specializing in meat alone may have a detrimental impact in your bone well being. As famous in a research revealed in Proceedings of the Diet Society,23 “It’s recognized that calcium excretion could rise with elevated protein consumption suggesting a detriment to bone mass.”

One of the best ways to get extra collagen into your eating regimen is by making bone broth from natural grass fed animal bones. Gradual-cooking or strain cooking extra gelatinous cuts of meat are an alternative choice, as are collagen and gelatin dietary supplements.

The Impression Precipitated Throughout Train Strengthens Your Bones

Most individuals are conscious that train helps enhance your total health and even lowers your threat of most cancers, diabetes and heart problems.24 Train can also be a foundational technique to strengthen your bones. As famous in a 2022 research revealed in Frontiers in Immunology,25 train reveals a constructive impact on osteoporosis. Particularly, the affect felt by your bones causes them to adapt, rework and strengthen themselves:

“Mechanical forces utilized to bone tissue induce the motion of interstitial fluid alongside tubules and bone cell pores, thereby inflicting cell-level shear stress and deformation of bone cell plasma membrane. These modifications result in the start of the bone reworking course of and stimulate bone resorption and formation cycles,” the research authors famous.

The researchers famous that resistance coaching, in addition to cardio coaching, positively advantages bone density by stimulating hormonal reactions to advertise stronger bone reformation.26 Along with these two, you additionally should take note of the depth of the workout routines you do. In accordance with one other research,27 train have to be dynamic, and inserting a load (reminiscent of weights) generates forces that may have a robust and constant constructive impact on bone growth.

KAATSU Improves Bone Density With out Lifting Heavy Weights

Whereas power coaching might be dangerous for the aged and people with already brittle bones, there is a technique to circumvent this threat. Blood circulate restriction coaching, significantly the KAATSU methodology, lets you get the advantages of resistance train with out the necessity for heavy weights.

KAATSU works by limiting blood circulate in your extremities in cycles, which creates intermittent hypoxia. This ends in the manufacturing of anti-inflammatory myokines that construct muscle power whereas lifting lighter weights, which is an enormous profit for individuals who have decrease mineral density and want to ease into exercising. In my interview with Steven Munatones, an professional KAATSU practitioner, he explains the way it works:

“KAATSU cycle is principally a really intelligent biohack that may enable the muscle mass to work and permit the vascular tissue to develop into extra elastic. You do not understand the ache of heavy lifting, however your vascular tissue and muscle fibers are being labored out simply as successfully, and you are able to do it for an extended time period.”

Furthermore, KAATSU will assist enhance bone mineral density, and this profit has been documented in research. In a single instance, revealed in Frontiers in Physiology,28 researchers noticed contributors who carried out BFR coaching for six weeks.

After the take a look at interval was full, outcomes revealed that even at low depth, BFR stimulated acute bone formation biomarkers. In one other research,29 researchers famous that low-intensity BFR train was simply as efficient as high-intensity train in decreasing biomarkers of bone destruction.

So, how do you incorporate KAATSU into your train routine? Merely put on the KAATSU bands whereas figuring out, both with or with out weights. For extra info, learn my article “Easy methods to Keep Match for Life.” You may discover an in-depth rationalization of how KAATSU works, in addition to particular workout routines that make the most of this superb train innovation.

Combine Up Your Train Routine with a Vibration Plate

Along with train and KAATSU, one other means of combatting osteoporosis is whole-body vibration (WBV) remedy. Basically, it is a methodology whereby vibrations are despatched all through your physique in small, managed doses. This causes constructive results in your physique, together with elevated bone mineral density. In a 2022 meta-analysis30 of 14 randomized managed trials, researchers famous that WBV remedy exhibited constructive results on sufferers with knee osteoarthritis (OA):

“Meta-analysis confirmed that low-frequency and high-frequency whole-body vibration had extra constructive results in contrast with strengthening workout routines alone on ache, knee extensor muscle power, and bodily perform in people with knee OA. Entire-body vibration with strengthening workout routines might be included into remedy protocols.”

One other meta-analysis31 revealed related outcomes. Right here, researchers confirmed that WBV remedy boosts bone mineral density in postmenopausal ladies and reduces the chance of bone fractures in wholesome adults. Aged individuals who intend to make use of a vibration plate to handle their osteoporosis will even take pleasure in different advantages, reminiscent of elevated cognition.32

For a better look into the mechanisms and historical past behind WBV remedy, learn my article “Make the most of the Energy of Vibrations to Promote Wellness.” There, I additionally focus on workout routines which are accomplished on a vibration plate, in addition to recommendations on how to decide on one of the best product on your wants.

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